中心简介:
主要开展妇科系统肿瘤(宫颈癌、子宫内膜癌、卵巢癌等)相关疾病的多学科诊疗、科研和教学工作,设有妇科肿瘤外科、妇科肿瘤内科、妇科肿瘤放疗等3个专科主诊组,负责患者阶段性专科诊疗;配备宫颈癌、卵巢癌、子宫癌等5个专病管理组,负责对患者进行全程管理。
特色诊疗:
1.女性下生殖道瘤变及癌变的光动力治疗
2.卵巢癌腹腔热灌注治疗
3.子宫内膜癌前哨淋巴结活检
4.宫颈癌三维后装联合组织间插植技术
5.卵巢癌靶向治疗及宫颈癌免疫治疗
科研攻关:
1.主要承担的科研项目
(1)大气压低温等离子体诱导宫颈癌细胞损伤及死亡方式研究,安徽省重点研发计划,2021
(2)宫颈癌联合放疗精准计量评估及其临床应用研究,安徽省重点研发计划,2018
(3)低温等离子体诱导人宫颈癌HeLa细胞凋亡的信号转导通路研究,安徽省自然科学基金,2014
2.代表性论文
(1)Dongyan Liu, Xiaonan Hou, Wangyu Wu, Valentina Zanfagnin, Yunjian Li, Cristina Correia, Zhiyang Zhao, Chenggang Zhao, Zhirong Liu, Tao Zhang, Zhiyou Fang, Hongzhi Wang, Chao Xu, Saravut J Weroha, Scott H Kaufmann, Haiming Dai. Constitutive BAK/MCL1 complexes predict paclitaxel and S63845 sensitivity of ovarian cance. Cell death & disease. 2021, 12(8): 789.
(2)Ao Xu, Wei Wang, Jinfu Nie, Vivian WY Lui, Bo Hong, Wenchu Lin. Germline mutation and aberrant transcripts of WWOX in a syndrome with multiple primary tumors. Journal of Pathology. 2019, 249(1): 19-25.
(3)Wei Li, K.N. Yu, Jie Ma, Jie Shen, Cheng Cheng, Fangjian Zhou, Zhiming Cai,Wei HanNon-thermal plasma induces mitochondria-mediated apoptotic signaling pathway via ROS generation in HeLa cells. Archives of
Biochemistry and Biophysics. 2017, 633: 68-77.
(4)Wenzhao Zhou, Chaoqun Huang, Xue Zou, Yan Lu, Chengyin Shen, Xiping Ding, Hongzhi Wang, Haihe Jiang, Yannan Chu. Exhaled breath online measurement for cervical cancer patients and healthy subjects by proton transfer reaction mass spectrometry. Analytical and Bioanalytical Chemistry. 2017, 409: 5603-5612.
(5)Ao Xu, Wei Wang, Jinfu Nie, Vivian WY Lui, Bo Hong, Wenchu Lin. Germline mutation and aberrant transcripts of WWOX in a syndrome with multiple primary tumors. Journal of Pathology. 2019, 249(1): 19-25.