中心简介：

主要开展乳腺肿瘤（乳腺癌、乳腺结节等）相关疾病的多学科诊疗、科研和教学工作，设有乳腺肿瘤外科、乳腺肿瘤内科、乳腺肿瘤放疗等3个专科主诊组，负责患者阶段性专科诊疗；配备4个乳腺癌专病管理组，负责对患者进行全程管理。

特色诊疗：

1.乳腺癌各种根治、保乳、再造（即刻或延期）术

2.乳腺癌新辅助或者辅助各种化疗、内分泌治疗、靶向治疗及免疫治疗

3.乳腺癌精确放疗技术

4.乳腺癌多学科综合诊疗

科研攻关：

1.主要承担的科研项目

（1）大气压低温等离子体对肿瘤细胞的损伤及致死机理研究，国家自然科学基金，2020

（2）直接激活细胞凋亡效应分子BAK的抗肿瘤药物前体研发，安徽省重点研发计划，2021

（3）电离辐射对肿瘤血管通透性的影响及机制研究，安徽省自然科学基金，2013

2.代表性论文

（1）Changfang Fu, Yu Liu, Xinghua Han, Yueyin Pan, Hongqiang Wang, Hongzhi Wang, Haiming Dai, Wulin Yang. An immune-associated genomic signature effectively predicts pathologic complete response to neoadjuvant paclitaxel and anthracycline-based chemotherapy in breast cancer. Frontiers In Immunology. 2021, 12: 704655.

（2）Jian Qi, Yu Liu, Jiliang Hu, Li Lu, Zhen Dou, Haiming Dai, Hongzhi Wang, Wulin Yang. Identification of FPR3 as a unique biomarker for targeted therapy in the immune microenvironment of breast cancer. Frontiers in Pharmacology. 2021, 11: 593247.

（3）Feng Qin, Qiang Fan, Peter K N Yu, Waleed Abdelbagi Almahi, Peizhong Kong, Miaomiao Yang, Wei Cao, Lili Nie, Guodong Chen, Wei Han. Properties and gene expression profiling of acquired radioresistance in mouse breast cancer cells. Annals of Translational Medicine. 2021, 9(8): 628.

（4）Yu Liu, Jian Qi, Zhen Dou, Jiliang Hu, Li Lu, Haiming Dai, Hongzhi Wang, Wulin Yang. Systematic expression analysis of WEE family kinases reveals the importance of PKMYT1 in breast carcinogenesis. Cell Proliferation. 2020, 53(2): e12741.

（5）Wen Li, Jingjing Zhao, Ke Ding, Herta H Chao, Chiang-Shan R Li, Huaidong Cheng, Li Shen. Catechol-O-Methyltransferase Gene Polymorphisms and the Risk of Chemotherapy-Induced Prospective Memory Impairment in Breast Cancer Patients with Varying Tumor Hormonal Receptor Expression. Medical Science Monitor. 2020, 26: e923567.